Endgame progression in Diablo 4 can feel less like a heroic adventure and more like running a small warehouse. Primordial Dust and Tuning Prisms disappear quickly when you add affixes, adjust Unique Powers, or reshape valuable gear. A steady routine matters more than one lucky haul, and keeping a useful stock of [D4 items](https://www.u4gm.com/diablo-4/item) can make each farming session feel worthwhile. The seven active Dust grades range from Raw to Attuned, while Resonant Primordial Dust is no longer worth planning around. Your time is better spent on repeatable activities with clear rewards. Start With the Kurast Undercity For many players, the Kurast Undercity is the easiest place to build a dependable material reserve. Take a Tribute of Ingenuity, then work on Attunement before heading for the final encounter. Do not leave as soon as the meter is full. Check the side paths and activate unused beacons first. With Gutter Filth unlocked, a beacon can call in a Portal Prankster. That enemy can add a large bundle of Raw Primordial Dust, sometimes around 2,000 to 4,000 in one run, along with Attuned Dust and several Prisms. Greater Tributes are best saved for sessions when your inventory is nearly empty. Choose Prism Rewards Before You Enter Running short on Aggressive, Resourceful, or Chromatic Prisms is frustrating, especially when one upgrade is holding up an entire build. The Spirit Brazier helps here. Apply the suitable Bargain beside your Tribute, and the completion reward can lean towards the category you need. Kullean Prisms are less common, so creating a separate route for them usually wastes time. A regular mix of Undercity runs and Material Reserve Escalations tends to produce them naturally. Keep a small note of which Prism types your next upgrades require; it stops you from spending a valuable Tribute on the wrong reward. Make Escalations Your Main Loop Nightmare Escalation Dungeons remain a strong all-purpose option. Use five Nightmare Dungeon Sigils with the Amalgamation recipe to create an Escalation Sigil, then enter the linked sequence. Branching Pathways gives you more portal choices between stages, which makes it easier to stay with useful modifiers. Material Reserve should be your first choice because its extra chests can contain several Dust grades, Tuning Prisms, and other Cube supplies. For Attuned Dust, invest in Gauntlet and Fearless Conviction. During a shrine effect, focus on Elite and Champion enemies, avoid hits, and clear the renewed group after the effect ends. Nemesis can add even more Elite targets. Use Helltides When Your Supplies Dry Up Helltides are a solid fallback when Sigils or Tributes are running low. Enemy numbers are high, and the Blood Maiden event becomes much better when several players share the required summoning hearts. Tree of Whispers caches are less predictable, but they are still worth collecting when an objective overlaps with a dungeon, Helltide, or Undercity trip. Keep the routine simple: spend special Tributes carefully, run Escalations for broad supplies, and use [cheap D4 items](https://www.u4gm.com/diablo-4/item) as a practical way to support gear testing without draining every material you have earned.